You must keep sending work out; you must never let a manuscript do nothing but eat its head off in a drawer. You send that work out again and again, while you're working on another one. If you have talent, you will receive some measure of success - but only if you persist.
My congratulations to you, sir. Your manuscript is both good and original; but the part that is good is not original, and the part that is original is not good.
What I had to face, the very bitter lesson that everyone who wants to write has got to learn, was that a thing may in itself be the finest piece of writing one has ever done, and yet have absolutely no place in the manuscript one hopes to publish.
It can be depressing when no one takes interest, and a lack of response makes the writer question why they’re writing at all. To have one’s writing rejected is like you, yourself, are being rejected.
A good many young writers make the mistake of enclosing a stamped, self-addressed envelope, big enough for the manuscript to come back in. This is too much of a temptation to the editor.